Archive for category the health

Ralph Lauren stick insect sacked for being ‘too fat’

Filippa-Hamilton

The model featured in the Ralph Lauren Photoshop stick insect outrage – in which she was Photoshopped to within an inch of her life – claims she was sacked by the company for being “too fat”.

ralph_lauren_photoshop

Filippa Hamilton suffered such an extreme digital makeover in an ad for the fashion company that BoingBoing was prompted to gasp: “Dude, her head’s bigger than her pelvis.”

Photoshopped model’s pelvis actually bigger than her head

Ralph Lauren quickly threw DMCA takedown notices at BoingBoing and PhotoshopDisasters for exposing the folly, but subsequently decided to apologise. It said in a statement: “For over 42 years, we have built a brand based on quality and integrity. After further investigation, we have learned that we are responsible for the poor imaging and retouching that resulted in a very distorted image of a woman’s body.

“We have addressed the problem and going forward will take every precaution to ensure that the calibre of our artwork represents our brand appropriately.”

Hamilton, 23, now claims she was in fact ditched by Ralph Lauren back in April, before the offending image surfaced, because she was “too large”. She said: “They fired me because they said I was overweight and I couldn’t fit in their clothes anymore.”

The model, who is 120lb and 5ft 10in tall, said she decided to go public after she saw the snap of her Photoshop-ravaged frame. She told the Today show: “I saw my face on this super-extremely skinny girl, which is not me; it’s not healthy, it’s not right.”

Ralph Lauren issued a further statement on Tuesday which claimed Hamilton was a “beautiful and healthy” woman and that her dismissal was “as a result of her inability to meet the obligations under her contract with us”. The company explained that the terms of the contract are confidential.

via Ralph Lauren stick insect sacked for being ‘too fat’ • The Register.

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Senior Citizens Help Young Children with Reading – and Relationships

Ageless Friendship: "Grandpa" Paul Bookout welcomes kindergarteners to school at Grace Living Center. Credit: Darren Parker

At the same time every morning, Paul Bookout sits impatiently in his wheelchair, looking out the front door of the Grace Living Center. Hes not waiting for family visitors, and hes not longing to be away from this nursing home. Hes waiting for the children. Just before 9 a.m., a stream of five-year-olds comes through the door, calling out greetings and hugging their “Grandpa Paul.” Though Bookout cant speak as a result of a stroke, he points and smiles with delight as he follows these kindergartners to the door of their classroom, here in the nursing home.

The Grace Living Center is home to two classrooms of about 60 kindergarten and prekindergarten students, as well as to 170 elders, who are “grandmas” and “grandpas” to the students. Kids attend the center in lieu of the first two grades at another school in the district, then switch at the start of first grade.

Far from just a heartwarming partnership, the school housed in the GLC provides students with daily mentors in their academic and social development, yielding proven results in reading and vocabulary. Its success has inspired the opening of a similar school in Kansas and is a model for intergenerational learning, even in more traditional settings.

The partnership came about in 1998, when Don Greiner, president of an Oklahoma nursing home chain, started construction on a facility in Jenks. Noticing a school district-owned daycare center next door, Greiner approached the district about upgrading the playground, thinking that the sight of kids playing could uplift his residents. The idea of a collaboration snowballed as the GLC and Jenks Public Schools found that their goals aligned.

The GLC works to eliminate loneliness, helplessness, and boredom in aging populations; the district’s curricular vision, says Shan Glandon, director of curriculum and instruction, is “to make learning as engaging and purposeful as we can,” focusing on integrating content with real-world ties. Eventually, all parties agreed to create two classrooms inside the nursing home; the GLC paid about $200,000 for construction and leased the space to the district for $1 a year.

School and nursing home are integrated in both physical design and curricular planning. Classrooms wrap around the beauty shop and between the GLC’s atrium and dining hall. Sliding glass doors open onto the hallway, and pane-free windows allow children’s voices to float through the home. Parents drop kids off at the GLC’s front door: They snake through the home to get to class. And elders maneuver their wheelchairs up to huge windows to watch kids play on the playground, or go out to the play area themselves.

To ensure curricular ties, the GLC employs a full-time liaison — the energetic Elaine Arnold — who identifies mentoring opportunities for every interested resident and is present any time kids are with elders. The district allocates time for Glandon to meet regularly with Arnold and the teachers, and every four to six weeks, the group reviews the curriculum taught in all 30 of the district’s kindergarten classes, identifies unit objectives, discusses skills they should reinforce, and brainstorms activities in which grandmas and grandpas can help students learn.

The curricular hallmark of the partnership is “book buddies,” which pairs rotating groups of elders and kindergarten students who read to one another for about 30 minutes several times a week. Grandpa Charles “Charlie” Lamson, who moved to the GLC after suffering a stroke, has participated for about a year. “I always start out saying, ‘Are you going to read to me?’ ” says Grandpa Charlie, a tall man wearing a Tulsa Drillers baseball cap. “It’s such a good feeling to just listen, read along, and help with words,” he explains. “I know how important it is to learn to read, and if I can read to them now, that’s a big help down the line.”

Grandpa Charlie is right. Since 2004, the Jenks Public Schools has tracked the number of students entering first grade whose reading skills are below grade level. Consistently, a smaller percentage of students from the GLC have required reading intervention once they entered first grade than those who attended prekindergarten or kindergarten at the nearby West Elementary School, which has a similar population but no intergenerational partners; for the last three years, the difference has been about 10 percent.

Another key program is “shared study,” in which elders join small groups of kindergartners in hands-on activities. On the day of my visit, Grandma Irene rolled her wheelchair up to a round table where a handful of kids were creating books of fall leaves. She talked about making Christmas ornaments from leaves as a child, and throughout the activity helped students measure, color, describe textures, and make rubbings. Earlier in the month, students had made scarecrows while elders talked about growing up on farms; they worked together guesstimating the circumference of pumpkins. During a unit on senses, residents helped with taste tests.

According to kindergartner Liam, “We do activities, like trying new food. I tried a mint leaf and dark chocolate. I like school better with grandmas and grandpas.”

Site principal Suzanne Lair says shared study is developmentally appropriate for both groups. “Things like cutting and pasting with the kids helps the residents not lose those motor skills,” she adds.

Dramatic play is also important, as residents join prekindergarten students in enacting a scenario connected to the unit of study. Using props and costumes to set the scene — like Thanksgiving dinner, a vacation, a trip to the doctor’s office — the teacher gets the ball rolling, then kids, grandmas, and grandpas begin improvising. “This is all in the service of language development, interacting with vocabulary,” says Lair.

To promote connections between the generations, teachers look at class themes through the lens of “then and now.” In the My Classroom unit, for instance, students and elders compared how they traveled to school; in Healthy Habits, they discussed lunch choices and options from the past and today. Sometimes those discussions become big books created by the students and elders.

Although all Jenks schools weave instruction of core values — compassion, responsibility, perseverance, for instance — into the curriculum, GLC students learn in an environment where those lessons are naturally reinforced. Lair says, “Students’ understanding of respect takes on a whole different meaning as they learn about respecting the individual homes of the grandmas and grandpas within the nursing home. They learn about responsibility and self-discipline when they see the grandmas and grandpas coming to read with them every day. They experience tolerance and acceptance of physical differences when there is a resident who carries an oxygen tank or has difficulty speaking.”

Instructors teach these core values explicitly, too. Following the Tribes program philosophy, in which a sense of safety and tribe-like community is incorporated into the classroom, teachers define and model ideas like “good listening.”

At the beginning of the school year, and before any new activity with elders, Arnold prepares kids with discussions, posters, and a review of the rules. “I say, ‘Grandpa Buddy was in the war and lost a leg. Should we talk about people without feet or legs?’ I let children share about that.” Mundane school rules have urgency at the GLC; students who don’t maintain ordered lines might be in the way of an ambulance worker with a gurney or a frail elder with a walker. Arnold says, “I tell them point blank, ‘If we knock Grandma down, she might break her hip.’”

Rich social and emotional learning comes as a response to the environment. Kids observe teachers greeting and touching the grandmas and grandpas, asking them questions. Prekindergarten students visit residents in their rooms, learning to knock and asking permission to enter. Arnold talks to children individually if they show any disrespect or lack of compassion. And death is dealt with head on. A few years ago, when a grandparent died, the class brainstormed how to support the family. “They ended up creating a book, with each child contributing a page about his or her best memory of the person,” says Lair. “They took a real-life event and applied skills they’d learned — in writing, storytelling, and compassion.”

“Here, we have elders, who our society has parked somewhere, having that impact. This is an opportunity for them to mean something and be something.”

Not only do kids learn about difference, illness, and aging in a supportive environment, but elders gain a real sense of purpose. “These kids are better readers because the grandmas and grandpas are there reading to them five days a week,” says GLC president Don Greiner. “Here, we have elders, who our society has parked somewhere, having that impact. This is an opportunity for them to mean something and be something.”

The relationships built in the academic work spill over into the home’s social events, too. Grandpa Charlie appreciates even the smallest acknowledgments from kids at weekly ice cream socials. “You’re sitting there eating and a kid you worked with in the morning will come up and ask, ‘What kind are you having, Grandpa Charlie?’ and it almost tears your heart out,” he says, choking up, “that they would remember me.”

Teachers, too, reap the benefits. “I’ve learned more about the stages in our lives,” says prekindergarten teacher Glenda Fitzgerald. “When you become a teacher, you want your kids to succeed, you want to see children learning and growing. The bonus here is that you also get to see the elders grow and learn. I get goose bumps about both.”

This article was also published in the February 2009 issue of Edutopia magazine as “No Generation Gap Here”.

A reference to this story was also included in the book ‘The Element – How finding your passion changes everything’ by Ken Robinson and Lou Aronica

via Senior Citizens Help Young Children with Reading — and Relationships | Edutopia.

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What’s Inside a Cup of Coffee?

drink-coffee

Caffeine

This is why the world produces more than 16 billion pounds of coffee beans per year. It’s actually an alkaloid plant toxin (like nicotine and cocaine), a bug killer that stimulates us by blocking neuroreceptors for the sleep chemical adenosine. The result: you, awake.

Water

Hot H2O is a super solvent, leaching flavors and oils out of the coffee bean. A good cup of joe is 98.75 percent water and 1.25 percent soluble plant matter. Caffeine is a diuretic, so coffee newbies pee out the water quickly; java junkies build up resistance.

2-Ethylphenol

Creates a tarlike, medicinal odor in your morning wake-up. It’s also a component of cockroach alarm pheromones, chemical signals that warn the colony of danger.

Quinic acid

Gives coffee its slightly sour flavor. On the plus side, it’s one of the starter chemicals in the formulation of Tamiflu.

3,5 Dicaffeoylquinic acid

When scientists pretreat neurons with this acid in the lab, the cells are significantly (though not completely) protected from free-radical damage. Yup: Coffee is a good source of antioxidants.

Dimethyl disulfide

A product of roasting the green coffee bean, this compound is just at the threshold of detectability in brewed java. Good thing, too, as it’s one of the compounds that gives human feces its odor.

Acetylmethylcarbinol

That rich, buttery taste in your daily jolt comes in part from this flammable yellow liquid, which helps give real butter its flavor and is a component of artificial flavoring in microwave popcorn.

Putrescine

Ever wonder what makes spoiled meat so poisonous? Here you go. Ptomaines like putrescine are produced when E. coli bacteria in the meat break down amino acids. Naturally present in coffee beans, it smells, as you might guess from the name, like Satan’s outhouse.

Trigonelline

Chemically, it’s a molecule of niacin with a methyl group attached. It breaks down into pyridines, which give coffee its sweet, earthy taste and also prevent the tooth-eating bacterium Streptococcus mutans from attaching to your teeth. Coffee fights the Cavity Creeps.

Niacin

Trigonelline is unstable above 160 degrees F; the methyl group detaches, unleashing the niacin—vitamin B3—into your cup. Two or three espressos can provide half your recommended daily allowance.

via What’s Inside a Cup of Coffee? .

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Stephen Hawking gives up academic title

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A new Lucasian Professor will be appointed in the near future

Professor Stephen Hawking has given up a prestigious academic title.

The physicist, who has motor neurone disease, is completing his last day as Cambridge University’s Lucasian Professor of Mathematics.

The university said it was policy for holders of the title to retire at 67 and Prof Hawking was 67 in January.

Prof Hawking, who is one of the world’s leading cosmologists, will continue working at the university and a new Lucasian Professor will be appointed.

Previous holders of the title, founded by MP Henry Lucas in 1663, include Sir Isaac Newton, Charles Babbage, Sir Joseph Larmor and Sir James Lighthill.

Prof Hawking, who began work in Cambridge in 1962 and has held the Lucasian Professorship since 1979, is a Fellow of Gonville and Caius College.

He gained fame following the publication of his best-selling book A Brief History of Time in 1988.

via BBC NEWS | UK | England | Cambridgeshire | Hawking gives up academic title.

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European Airline Brings Back the Smoking Section

Photo: Ron Layters/Flickr

It’s been a long time since passengers have been allowed to smoke on an airliner in the United States. It’s the same story in Europe. But now the smoking crowd across the Atlantic have an option when the nicotine comes calling.

Ireland-based Ryanair is selling smokeless cigarettes on all the company’s flights. Ryanair says a survey showed more than 24,000 passengers would like the option to smoke during flights and that was enough of an incentive in these lean times to try and gain some market share as well as some extra income. So as long as you’re at least 18 years old, the company will sell you a pack of smokeless smokes for 6 euro (about $8.75).

Ryanair is a discount airlines that flies throughout Europe and North Africa and is no stranger to using a gimmick to bring in  some business. The company says the cigarettes can’t be lit and deliver the nicotine through inhalation.

For those who fear the old days when the difference between the smoking section on an airplane and the non-smoking section was simply whichever way the air was flowing inside the cabin, the smokeless cigarettes do not emit any toxins or chemicals to nearby passengers. Company spokesman Stephen McNamara believes when smokers can get their nicotine, everybody wins, “as these cigarettes are smokeless, they cause no discomfort to other passengers and can ensure a more enjoyable and stress-free flight for all passengers as non-smokers will no longer have to cope with moody smokers in need of nicotine.”

via European Airline Brings Back the Smoking Section | Autopia | Wired.com.

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Dandelion the Super Weed

Gummi aus Löwenzahn

Dandelion is currently being looked into as a source for rubber, as well as ethanol.

Ethanol can be made from inulin, an artificial sweetener found in the dandelion root. The inulin is fermented and made into ethanol. 1 million dandelion plants per acre will yield about 245 gallons of ethanol per planting.

Most natural rubber comes from rubber trees in Southeast Asia, but this source is now under threat from a fungus. Researchers have optimized the Russian dandelion to make it suitable for large-scale rubber production.

Anyone who has picked dandelions as a child will be familiar with the white liquid that seeps out of the stalks as you break them off. Viscous, sticky – and a much sought-after material: natural latex. Around 30,000 everyday products contain natural rubber, everything from car tires, catheter tubes, latex gloves to tops for drinks bottles. Car tires, for instance, would not be elastic enough without the incorporation of natural rubber. The bulk of this material comes from rubber trees in Southeast Asia. Rubber produced in this way can, however, cause allergic reactions, which is clearly an issue with clinical products. A fungus is also creating concern for rubber cultivators. In South America the infection is now so widespread that large-scale cultivation has become virtually impossible. The disease now also appears to have taken root in Southeast Asia’s rubber belt. Fungicides still provide at least temporary protection. But if the fungus disease was to reach epidemic proportions, chemical crop protection would be rendered useless – experts fear that the natural latex industry could collapse if that were to happen.

Researchers are therefore turning to other sources – such as the Russian dandelion. Germans, Russians and Americans produced rubber from this plant during the Second World War. Once it is cut, latex seeps out, albeit difficult to use as it polymerizes immediately. Scientists from the Fraunhofer Institute for Molecular Biology and Applied Ecology IME in Aachen have now come a step nearer to large-scale rubber production from dandelions. “We have identified the enzyme responsible for the rapid polymerization and have switched it off,” says Prof. Dr. Dirk Prüfer, Head of Department at the IME. “If the plant is cut, the latex flows out instead of being polymerized. We obtain four to five times the amount we would normally. If the plants were to be cultivated on a large scale, every hectare would produce 500 to 1000 kilograms of latex per growing season.” The dandelion rubber has not caused any allergies so far, making it ideal for use in hospitals.

In the lab the researchers have genetically modified the dandelion. Their next step will involve cultivating the optimized plants using conventional breeding techniques. In around five years, Prüfer estimates, they may well have achieved their goal. In any case, the dandelion is not just suitable for rubber production: the plant also produces substantial quantities of inulin, a natural sweetener.

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Warning: Showers can seriously damage your health

Geeks proved right after all

US scientists have rather disturbingly provided ammunition for shower-dodging geeks to defend their malodorous ways: showers can actually be bad for your health.

According to researchers at the University of Colorado at Boulder, pathogens which occur naturally at low levels in water supplies can accumulate in high concentrations in “biofilms” inside shower heads, meaning that every time you turn on the water, you’re getting a faceful of nastiness.

Specifically, the scientists pinpointed Mycobacterium avium – “a pathogen linked to pulmonary disease that most often infects people with compromised immune systems but which can occasionally infect healthy people”, according to lead boffin professor Norman Pace.

The team probed 50 shower heads from nine cities in seven states, including Chicago, Denver and New York City. In 30 per cent of them they found “significant levels” of Mycobacterium avium and related oathogens – specifically, “more than 100 times the background levels of municipal water”.

Pace said: “There have been some precedents for concern regarding pathogens and showerheads. But until this study we did not know just how much concern.”

He warned: “If you are getting a face full of water when you first turn your shower on, that means you are probably getting a particularly high load of Mycobacterium avium, which may not be too healthy.”

The University of Colorado seems to have an unhealthy interest in Mycobacterium avium. It previously “found massive enrichments of M. avium in ‘soap scum’ commonly found on vinyl shower curtains and floating above the water surface of warm therapy pools”.

In 2006, Pace plunged again into therapy pools, and identified “high levels of M. avium in the indoor pool environment were linked to a pneumonia-like pulmonary condition in pool attendants known as ‘lifeguard lung’”.

This in turn led Pace and chums to dismantle the US’s shower heads, the results of which investigations are found in the 14 September issue of Proceedings of the National Academy of Sciences (abstract here, more background detail here)

Naturally, you’re all wondering whether taking a shower is actually dangerous. Pace concluded: “Probably not, if your immune system is not compromised in some way. But it’s like anything else – there is a risk associated with it.”

The professor suggested using a metal showerhead, since the plastic type are apparently susceptible to biofilm build-up. Consider yourselves advised. ®

Bootnote

Here’s how the Colorado Uni boffins sniffed out their prey: “A molecular genetics technique developed by Pace in the 1990s allowed researchers to swab samples directly from the shower heads, isolate DNA, amplify it using the polymerase chain reaction, or PCR, and determine the sequences of genes present in order to pinpoint particular pathogen types.”

via Warning: Showers can seriously damage your health • The Register.

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Low lead levels harming children

Lead is linked to a number of health problems

Young childrens exposure to lead in the environment is harming their intellectual and emotional development, according to UK researchers.The researchers say the toxic effects of lead on the central nervous system are obvious even below the current so-called safe level of lead in the blood.They are recommending the threshold should be halved.A spokesman for the Health Protection Agency said levels of exposure should be kept to the minimum.Lead has been removed from paint and petrol by law in the UK, but it is still widespread in the environment.The study from the University of Bristol Centre for Child and Adolescent Health set out to see if there was any effect on the behaviour and intellectual development of children who had ingested just below the so-called safe level of 10 microgrammes per decilitre or tenth of a litre of blood.The study is published in the journal, Archives of Diseases in Childhood.

SOURCES OF LEAD

  • Lead-based paint
  • Household dust
  • Lead water pipes
  • Soil around the home
  • Paint on childrens toys
  • Childrens bead necklaces
  • Christmas lights
  • Lead smelters/industries

Lead levels

The Bristol researchers took blood samples from 582 children at the age of 30 months.They found 27% of the children had lead levels above five microgrammes per decilitre.They followed the childrens progress at regular intervals and then assessed their academic performance and behavioural patterns when they were seven to eight years old.After taking account of factors likely to influence the results, they found that blood lead levels at 30 months showed significant associations with educational achievement, antisocial behaviour and hyperactivity scores five years later.With lead levels up to five microgrammes per decilitre, there was no obvious effect.But lead levels between five and 10 microgrammes per decilitre were associated with significantly poorer scores for reading 49% lower and writing 51% lower.A doubling in lead blood levels to 10 microgrammes per decilitre was associated with a drop of a third of a grade in their Scholastic Assessment Tests SATs.And above 10 microgrammes per decilitre children were almost three times as likely to display antisocial behaviour patterns and be hyperactive than the children with the lower levels of lead in their blood.Adverse effectsThe effects of lead toxicity in children were first described in 1892 in Brisbane, Australia. The Agencys advice is that exposures to lead should be kept to the minimum that is reasonably practical Health Protection Agency spokesmanSince then acceptable levels of lead in the blood have fallen sharply.In 1991, the US Centres for Disease Control and Prevention, revised their level of concern for blood levels down to ten microgrammes per declitre.The World Health Organisation estimates that globally half of the urban children under the age of five have blood levels exceeding this limit.Professor Alan Emond, who led this study, said a third of the children in his study had levels only half of this but were still exhibiting adverse effects.He said: “Lead in the body is one of many factors that impacts on education, but this is a reminder that environmental factors are important and paediatricians must test more children with behavioural problems for lead.”"We did our blood survey when the children were about two and a half years old.”We think this is quite close to the peak age for lead ingestion when the children are putting everything in their mouths as they explore their environment.”This is a normal phase that we grow out of, but for children who have developmental problems, like autism, it may go on for a longer time so they may be particularly vulnerable. “A Health Protection Agency spokesman said: “The Agencys advice is that exposures to lead should be kept to the minimum that is reasonably practical.”This has been the policy in the UK and of health agencies throughout the world for many years.”Measurements have shown that levels of lead in children and adults have decreased markedly over the last two decades or more, primarily because of these policies.”

via BBC NEWS | Health | Low lead levels harming children.

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Best Non-Candy Halloween Treats

Easy Ways to Avoid Handing Out Candy and Making Healthy Options Available for the Trick-or-treaters Who Tap at Your Door

With childhood obesity and juvenile diabetes on the rise, not to mention the high prices for candy this year, Halloween is the ideal time to get off the candy habit and hand out something healthier for the little ghouls and goblins who tap at your door this Halloween.

Since candy adds to obesity problems, can cause dental problems the least of which are cavaties, make children hyper on a sugar rush, contribute to the traditional Halloween tummyache, and contribute to other health issues, take charge and change over from candy.

One of the best traditional treats for Halloween that isn’t candy are popcorn balls. Back when I was growing up, many folks still made home made popcorn balls but today I would suggest the inexpensive, ready made popcorn balls found in stores. Each is individually wrapped and the cost is very low. Popcorn is a healthy food and popcorn balls pack a whole lot less sugar and calories than candy. Look for popcorn balls near the snack aisle or special Halloween section of your favorite supermarket or discount store.

Another popcorn alternative would be to hand out individual bags of microwave popcorn that kids can take home to pop later. These are cheap and no sugar!

Granola bars are another easy option. Look for granola bars with the healthiest ingredients. Quaker markets several lower sugar granola bars that have all the taste but far less sugar. Most granola bars are healthy but be sure to check the ingredients to be sure you’re not passing out something with as much sugar as candy.

Cereal bars are a newer popular option instead of candy. Most of us know about Rice Krispy bars because our moms and grandmas made them from the recipe on the box but did you know that today you can buy Rice Krispy bars in individually wrapped servings by the box? And in additon to the traditional flavor, they also are available in other flavors that include both chocolate and strawberry.

Other cereal bars available include the very popular Special K bars. I eat these all the time as a low calorie, low sugar snack and so my kids. They are also available individually wrapped in several flavors, drizzled with chocolate is one of my favorites.

Although the cost isn’t as low, fresh fruit – like apples – are another old-fashioned popular Halloween treat. Kids who get fresh fruit in their goodie bag are advised to have mom or dad wash, then cut the apple into section or slices before eating just in case some meanie has pulled the old “razor blade” trick but other than that, fresh fruit is a great alternative to candy for Halloween.

Peanuts and other nuts are another idea. These are available in indivual packages as well. So are sunflower seeds!

Animal crackers are another traditional kid friendly favorite. And these also come in individual serving sizes within a large box. They are low in fat, limited in sugar, and high on taste. Both frosted and unfrosted versions are available just about everywhere.

Or opt for cookie snacks, staying with types of cookies that are not totally loaded with sugar. Check the snack aisle for various individual serving packages of cookies and share the love with favorites like Oreos or Chips Ahoy!

String cheese is something else kids love to eat. Look for it in the grocer’s dairy case. Each cheese string is invidually wrapped and they come in large bags. Kids can enjoy these favorites without worrying about sugar and they are healthy!

It may sound silly but how about handing out individual boxes of kid-friendly cereal? Multi packs are available at just about every supermarket and tossing a small box of cereal in a kid’s trick or treat sack gives the little one something nutritious for breakfast!

There are many ways to opt for something besides candy this Halloween and these choices are all tasty, easy on the budget, have little or no sugar, and are great alternative choices to handing out candy for Halloween!!!!

via Best Non-Candy Halloween Treats « zikkir.

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New drug ‘can treat more cancers’

A promising new drug may be able to treat more types of cancer than first thought.

PARP inhibitors have shown early promise for treating cancers linked to BRCA gene mutations, including some breast and ovarian cancers.

But Breakthrough Breast Cancer research suggests they might also kill cancer cells with a faulty PTEN gene, found in some skin, womb and colon tumours.

The study appears in the journal EMBO Molecular Medicine.

Scientists found that cells with faulty PTEN genes were up to 25 times more sensitive to PARP inhibitors than cells with normal PTEN.

Faults in the PTEN gene account for 30%-80% of breast, prostate, melanoma (skin), womb and colon cancers.

Professor Alan Ashworth, director of the Breakthrough Breast Cancer Research Centre at the Institute of Cancer Research, said: “These results are exciting because they show that PARP inhibitors are potentially a powerful targeted treatment with few side effects which may help a broad range of cancer patients.

“Clinical trials have already shown the potential of PARP inhibitors for patients with tumours caused by faulty BRCA genes.

“We now need to test whether the promising results from this study can be matched in the much larger group of patients with PTEN-related tumours.”

Synthetic lethality

The use of PARP inhibitors is part of a new approach to cancer therapy called synthetic lethality.

A cell with a PTEN fault relies on a protein called PARP to keep its DNA undamaged.

PARP inhibitors work by blocking PARP, and when combined with defective PTEN, causes the cancer cell to die.

This means the tumour should either stop growing or get smaller.

Because the drug has a precise method of action it only affects cancer cells, leaving healthy cells unaffected, and minimising the risk of side effects.

PARP inhibitors have already produced impressive results when tested on patients with advanced breast, ovarian and prostate cancer caused by defects in the BRCA1 and BRCA2 genes.

In a recent clinical trial more than half of the patients’ tumours shrank or stabilised, despite the fact that they had not responded well to standard therapies.

One of the first patients to be given the treatment is still in remission after two years.

Lead researcher Dr Chris Lord said: “This new class of drugs could potentially make a big difference for many thousands of cancer patients, including some with very limited treatment options.”

via BBC NEWS | Health | New drug ‘can treat more cancers’.

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